Micky van de Ven Brace Ends The Toffees' Run at New Stadium
The Dutch defender became the initial backline player to score two goals in a Premier League game for Tottenham since the Belgian defender in March 2013.
At a glance
The Spurs defender heads into the net twice in opening period
The home side's Jake O'Brien has equalizer disallowed after video check
Senegalese midfielder nets third in 89th minute
The defeat is the Merseyside club's first at their new ground
Micky van de Ven scored twice as Spurs extended their unbeaten run on the road in the Premier League and delivered the Toffees their initial loss at Hill Dickinson Stadium.
Everton were undefeated in their five previous fixtures at their recently opened stadium at Bramley-Moore Dock, having left their historic home behind after more than a century at the conclusion of the previous campaign.
But Tottenham's leader Van de Ven struck on two occasions from corners in the opening 45 minutes to put their strong form at risk, and they were failed to mount a comeback before Pape Matar Sarr - assisted by former Toffees attacker Richarlison - headed home a final goal to seal the victory.
Jake O'Brien believed he had levelled the scores a short while after Van de Ven's first goal, directing a bullet header past Guglielmo Vicario from an set-piece.
Beto, meanwhile, failed to convert a number of chances, while Vicario made a succession of fine saves to ensure the London club went five matches on the road without defeat in the Premier League.
But the video assistant referee stepped in, advising the match official to check the goal on the screen and the referee decided that the winger and Iliman Ndiaye were in an illegal position and had interfered with the Tottenham goalkeeper.
The win moves Thomas Frank's side up to third in the Premier League, five points off local foes and leaders Arsenal.
Everton remain 14th and are six points ahead of the relegation zone.
Tottenham analysis: Van de Ven excels in duties at both ends of the field
After a uninspiring midweek performance in the Champions League against Monaco, where they mustered a only attempts on goal, the manager opted for Randal Kolo Muani up front instead of former Toffees player Richarlison.
The summer signing was unable to make much of an impact before being replaced for Richarlison after 60 minutes on the field, but it emerged he proved unnecessary in the end.
Defender the Dutchman converted into an attacking force to be reckoned with.
Tottenham's opening strike came from a cleverly executed corner routine, with the midfielder heading the ball toward the face of goal for an free Van de Ven to head home.
And Ven de Ven - filling in as skipper in the Argentine's unavailability - notched his next goal in added time as he rose above the England keeper to head home.
The Dutchman was just as outstanding in defensive duties, partnering well with his defensive colleague as the pair dealt excellently with the 34 crosses thrown their way by the opposition.
Everton analysis: Toffees missing finishing touch
The club's recent stadium had been a happy hunting ground, but it seems the novelty may have faded slightly and fans flocked to the exits after the midfielder's third for Tottenham.
The break in Everton's winning streak at home won't be a massive concern for the manager, but their striker situation are.
The forward and the other striker - the Toffees' two recognised centre-forwards - had netted just a single goal between them before Sunday's outing.
And they were unable to add to that miserable record on a wet and gloomy evening on Merseyside.
Beto's form was summed up when he opted to bicycle-kick a golden opportunity from near the goal, even with having room and opportunity to readjust for a simpler attempt that would have challenged the keeper.
The substitute, too, was unable to influence the game after coming on for the starter in the second half.
It was not for a shortage of opportunity. Most of Everton's attacks came through the winger and Ndiaye, who relentlessly whipped dangerous crosses into the Spurs box.
Upcoming fixtures for these two sides?
The Toffees: The team head to the Stadium of Light in the top flight on Monday, 3 November at 8 PM.
Tottenham: The London club travel to Newcastle's ground on Wednesday, 29 October for their fourth-round Carabao Cup tie against Newcastle.